Characterisation of 11beta-hydroxysteroid dehydrogenase 1 in human orbital adipose tissue: a comparison with subcutaneous and omental fat.

Glucocorticoids (GCs) have a profound effect on adipose biology increasing tissue mass causing central obesity. The pre-receptor regulation of GCs by 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) that activates cortisol from cortisone has been postulated as a fundamental mechanism underly...

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Príomhchruthaitheoirí: Bujalska, I, Durrani, O, Abbott, J, Onyimba, C, Khosla, P, Moosavi, A, Reuser, T, Stewart, P, Tomlinson, J, Walker, E, Rauz, S
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: 2007