A core human primary tumor angiogenesis signature identifies the endothelial orphan receptor ELTD1 as a key regulator of angiogenesis.
Limited clinical benefits derived from anti-VEGF therapy have driven the identification of new targets involved in tumor angiogenesis. Here, we report an integrative meta-analysis to define the transcriptional program underlying angiogenesis in human cancer. This approach identified ELTD1, an orphan...
Hoofdauteurs: | , , , , , , , , , , , , , , , , , , , , |
---|---|
Formaat: | Journal article |
Taal: | English |
Gepubliceerd in: |
Elsevier
2013
|