Asymmetric remote C-H functionalization: use of internal olefins in tandem hydrometallation-isomerization-asymmetric conjugate addition sequences
We describe catalytic asymmetric C-C formation using terminal alkyl-metal nucleophiles generated from internal olefins through a 'chain-walking' isomerization mechanism. Hydrometallation of internal olefins with the Schwartz reagent gives the least hindered alkyl-zirconocene after thermal...
| Glavni autori: | , , |
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| Format: | Journal article |
| Izdano: |
CSIRO Publishing
2015
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