AIM2 inflammasome is activated by pharmacological disruption of nuclear envelope integrity

AIM2 inflammasome is activated by pharmacological disruption of nuclear envelope integrity

Inflammasomes are critical sensors that convey cellular stress and pathogen presence to the immune system by activating inflammatory caspases and cytokines such as IL-1β. The nature of endogenous stress signals that activate inflammasomes remains unclear. Here we show that an inhibitor of the HIV as...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Di Micco, A, Frera, G, Lugrin, J, Jamilloux, Y, Hsu, E, Tardivel, A, De Gassart, A, Zaffalon, L, Bujisic, B, Siegert, S, Quadroni, M, Broz, P, Henry, T, Hrycyna, C, Martinon, F
Format: Journal article
Sprache:English
Veröffentlicht: National Academy of Sciences 2016

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