AIM2 inflammasome is activated by pharmacological disruption of nuclear envelope integrity

AIM2 inflammasome is activated by pharmacological disruption of nuclear envelope integrity

Inflammasomes are critical sensors that convey cellular stress and pathogen presence to the immune system by activating inflammatory caspases and cytokines such as IL-1β. The nature of endogenous stress signals that activate inflammasomes remains unclear. Here we show that an inhibitor of the HIV as...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính:	Di Micco, A, Frera, G, Lugrin, J, Jamilloux, Y, Hsu, E, Tardivel, A, De Gassart, A, Zaffalon, L, Bujisic, B, Siegert, S, Quadroni, M, Broz, P, Henry, T, Hrycyna, C, Martinon, F
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	National Academy of Sciences 2016

Những quyển sách tương tự

Taking AIM at Influenza: The Role of the AIM2 Inflammasome
Bằng: Dianne W. Xu, et al.
Được phát hành: (2024-09-01)

The aspartyl protease DDI2 drives adaptation to proteasome inhibition in multiple myeloma
Bằng: Mélanie Op, et al.
Được phát hành: (2022-05-01)

The Role of AIM2 Inflammasome in Knee Osteoarthritis
Bằng: Yang J, et al.
Được phát hành: (2022-11-01)

Roles of AIM2 Gene and AIM2 Inflammasome in the Pathogenesis and Treatment of Psoriasis
Bằng: Jieyi Wang, et al.
Được phát hành: (2022-09-01)

Inflammasomes in Host Defense and Autoimmunity
Bằng: Petr Broz
Được phát hành: (2016-12-01)

Activation and Pharmacological Regulation of Inflammasomes
Bằng: Chen Chen, et al.
Được phát hành: (2022-07-01)

Detection of ASC Oligomerization by Western Blotting
Bằng: Jérôme Lugrin, et al.
Được phát hành: (2017-05-01)

The protease DDI2 regulates NRF1 activation in response to cadmium toxicity
Bằng: Sérgio T. Ribeiro, et al.
Được phát hành: (2022-10-01)

The AIM2 inflammasome is activated in astrocytes during the late phase of EAE
Bằng: William E. Barclay, et al.
Được phát hành: (2022-04-01)

Role of the AIM2 Inflammasome in Cancer: Potential Therapeutic Strategies
Bằng: Chiara Colarusso, et al.
Được phát hành: (2025-02-01)

Mitochondrial ROS potentiates indirect activation of the AIM2 inflammasome
Bằng: Deborah D Crane, et al.
Được phát hành: (2014-08-01)

Pharmacological Inhibitors of the NLRP3 Inflammasome
Bằng: Ayesha Zahid, et al.
Được phát hành: (2019-10-01)

COVID-19: lipid disruption is pushing the envelope
Bằng: Garret A. FitzGerald
Được phát hành: (2022-07-01)

AIM2-inflammasome role in systemic lupus erythematous and rheumatoid arthritis
Bằng: E. E. Uresti-Rivera, et al.
Được phát hành: (2022-09-01)

AIM2 Inflammasome's First Decade of Discovery: Focus on Oral Diseases
Bằng: Lufei Wang, et al.
Được phát hành: (2020-08-01)

ER-trafficking triggers NRF1 ubiquitination to promote its proteolytic activation
Bằng: Claire Chavarria, et al.
Được phát hành: (2023-10-01)

Molecular Mechanism for p202-Mediated Specific Inhibition of AIM2 Inflammasome Activation
Bằng: Qian Yin, et al.
Được phát hành: (2013-07-01)

Assembly mechanism of the inflammasome sensor AIM2 revealed by single molecule analysis
Bằng: Meenakshi Sharma, et al.
Được phát hành: (2023-12-01)

Discovery of an inhibitor of DNA-driven inflammation that preferentially targets the AIM2 inflammasome
Bằng: Jack P. Green, et al.
Được phát hành: (2023-05-01)

Tyrosine Dephosphorylation of ASC Modulates the Activation of the NLRP3 and AIM2 Inflammasomes
Bằng: Bezaleel Mambwe, et al.
Được phát hành: (2019-07-01)

AIM2 inflammasome activation benefits the therapeutic effect of BCG in bladder carcinoma
Bằng: Houhong Zhou, et al.
Được phát hành: (2022-10-01)

The DNA-sensing AIM2 inflammasome controls radiation-induced cell death and tissue injury
Bằng: Hu, Bo, et al.
Được phát hành: (2018)

Pharmacological intervention of curcumin via the NLRP3 inflammasome in ischemic stroke
Bằng: Xiaoxue Du, et al.
Được phát hành: (2023-10-01)

Cytoplasmic DNA and AIM2 inflammasome in RA: where they come from and where they go?
Bằng: Conghui Xu, et al.
Được phát hành: (2024-10-01)

PKM2-dependent glycolysis promotes NLRP3 and AIM2 inflammasome activation
Bằng: Min Xie, et al.
Được phát hành: (2016-10-01)

Shikonin Suppresses NLRP3 and AIM2 Inflammasomes by Direct Inhibition of Caspase-1.
Bằng: Jernej Zorman, et al.
Được phát hành: (2016-01-01)

Perfluoroalkyl substance pollutants activate the innate immune system through the AIM2 inflammasome
Bằng: Li-Qiu Wang, et al.
Được phát hành: (2021-05-01)

AIM2 Engages Active but Unprocessed Caspase-1 to Induce Noncanonical Activation of the NLRP3 Inflammasome
Bằng: Larissa D. Cunha, et al.
Được phát hành: (2017-07-01)

Disruption of glycolytic flux is a signal for inflammasome signaling and pyroptotic cell death
Bằng: Laura E Sanman, et al.
Được phát hành: (2016-03-01)

Dual Engagement of the NLRP3 and AIM2 Inflammasomes by Plasmodium-Derived Hemozoin and DNA during Malaria
Bằng: Parisa Kalantari, et al.
Được phát hành: (2014-01-01)

The mechanism of NLRP3 inflammasome activation and its pharmacological inhibitors
Bằng: Xiaoyan Zhan, et al.
Được phát hành: (2023-01-01)

Therapeutic Potential of Pharmacological Targeting NLRP3 Inflammasome Complex in Cancer
Bằng: Gulcin Tezcan, et al.
Được phát hành: (2021-02-01)

The recombinant BCG ΔureC::hly vaccine targets the AIM2 Inflammasome to induce autophagy and inflammation
Bằng: Saiga, H, et al.
Được phát hành: (2014)

The impact of AIM2 inflammasome-induced pyroptosis on acute gouty arthritis and asymptomatic hyperuricemia patients
Bằng: Jiyan Chu, et al.
Được phát hành: (2024-07-01)

A novel role of AIM2 inflammasome-mediated pyroptosis in radiofrequency ablation of hepatocellular carcinoma
Bằng: Feifan He, et al.
Được phát hành: (2024-11-01)

Artemisia Extract Suppresses NLRP3 and AIM2 Inflammasome Activation by Inhibition of ASC Phosphorylation
Bằng: Su-Bin Kwak, et al.
Được phát hành: (2018-01-01)

TUDCA alleviates atherosclerosis by inhibiting AIM2 inflammasome and enhancing cholesterol efflux capacity in macrophage
Bằng: Xuyang Wang, et al.
Được phát hành: (2024-06-01)

Correction: Shikonin Suppresses NLRP3 and AIM2 Inflammasomes by Direct Inhibition of Caspase-1.
Bằng: Jernej Zorman, et al.
Được phát hành: (2016-01-01)

Effects of serum-clot contact time on second-trimester prenatal screening markers and their stability in serum
Bằng: Bujišić Nada
Được phát hành: (2010-01-01)

Breaking barriers: noncanonical inflammasome executes blood–brain barrier disruption
Bằng: Martin Dichgans, et al.
Được phát hành: (2024-08-01)