Involvement of ADAMTS5 and hyaluronidase in aggrecan degradation and release from OSM-stimulated cartilage.
The relative contribution of a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS)4 and ADAMTS5 to aggrecan degradation under oncostatin M (OSM) stimulation, the role of the ancillary domains of the aggrecanases on their ability to cleave within the chondroitin sulfate (CS)-2 regio...
Main Authors: | Durigova, M, Troeberg, L, Nagase, H, Roughley, P, Mort, J |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2011
|
Similar Items
-
Characterization of an ADAMTS-5-mediated cleavage site in aggrecan in OSM-stimulated bovine cartilage.
by: Durigova, M, et al.
Published: (2008) -
MMPs are less efficient than ADAMTS5 in cleaving aggrecan core protein.
by: Durigova, M, et al.
Published: (2011) -
The role of aggrecan in normal and osteoarthritic cartilage
by: Peter J Roughley, et al.
Published: (2014-01-01) -
Isolation of fibronectin fragments that induce aggrecan degradation in cartilage
by: Sofat, N, et al.
Published: (2006) -
What is the minimal length of calcium pentosan polysulfate that is able to block aggrecan breakdown in cartilage?
by: Troeberg, L, et al.
Published: (2009)