Relationship between E23K (an established type II diabetes-susceptibility variant within KCNJ11), polycystic ovary syndrome and androgen levels.

Polycystic ovary syndrome (PCOS) is strongly associated with hyperinsulinaemia and type II diabetes (T2D). Sequence variation within KCNJ11 (encoding Kir6.2, the beta-cell inwardly rectifying potassium channel) is implicated in the pathogenesis of neonatal diabetes, hyperinsulinaemia of infancy and...

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Bibliographic Details
Main Authors: Barber, T, Bennett, A, Gloyn, A, Groves, C, Sovio, U, Ruokonen, A, Martikainen, H, Pouta, A, Taponen, S, Weedon, M, Hartikainen, A, Wass, J, Järvelin, MR, Zeggini, E, Franks, S, McCarthy, M
Format: Journal article
Language:English
Published: 2007