Genetic association analysis of inositol polyphosphate phosphatase-like 1 (INPPL1, SHIP2) variants with essential hypertension.

BACKGROUND: Inositol polyphosphate phosphatase-like 1 (INPPL1, SHIP2) is a negative regulator of insulin signalling and has previously been found to be associated with hypertension, obesity and type 2 diabetes in a cohort of families with diabetes in the UK presenting features of metabolic syndrome....

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Main Authors: Marçano, A, Burke, B, Gungadoo, J, Wallace, C, Kaisaki, P, Woon, P, Farrall, M, Clayton, D, Brown, M, Dominiczak, A, Connell, J, Webster, J, Lathrop, M, Caulfield, M, Samani, N, Gauguier, D, Munroe, P
Format: Journal article
Language:English
Published: 2007