Structure of proline 3-hydroxylase. Evolution of the family of 2-oxoglutarate dependent oxygenases.
Iron (II)/2-oxoglutarate (2-OG)-dependent oxygenases catalyse oxidative reactions in a range of metabolic processes including the hydroxylation of proline and lysine residues during the post-translational modification of collagen. 2-OG oxygenases commonly require ascorbate for full activity. In the...
主要な著者: | Clifton, I, Hsueh, L, Baldwin, J, Harlos, K, Schofield, C |
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フォーマット: | Journal article |
言語: | English |
出版事項: |
2001
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