Structure of proline 3-hydroxylase. Evolution of the family of 2-oxoglutarate dependent oxygenases.

Structure of proline 3-hydroxylase. Evolution of the family of 2-oxoglutarate dependent oxygenases.

Iron (II)/2-oxoglutarate (2-OG)-dependent oxygenases catalyse oxidative reactions in a range of metabolic processes including the hydroxylation of proline and lysine residues during the post-translational modification of collagen. 2-OG oxygenases commonly require ascorbate for full activity. In the...

Bibliográfalaš dieđut
Váldodahkkit:	Clifton, I, Hsueh, L, Baldwin, J, Harlos, K, Schofield, C
Materiálatiipa:	Journal article
Giella:	English
Almmustuhtton:	2001

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Mechanistic studies on 2-oxoglutarate dependent oxygenases
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Structural studies on human 2-oxoglutarate dependent oxygenases.
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Almmustuhtton: (2010)

2-oxoglutarate-dependent oxygenases
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Almmustuhtton: (2011)

Structural and mechanistic studies on 2-oxoglutarate-dependent oxygenases and related enzymes.
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Autocatalysed oxidative modifications to 2-oxoglutarate dependent oxygenases
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Almmustuhtton: (2012)

Autocatalysed oxidative modifications to 2-oxoglutarate dependent oxygenases
Dahkki: Mantri, M, et al.
Almmustuhtton: (2012)

Autocatalysed oxidative modifications to 2-oxoglutarate dependent oxygenases.
Dahkki: Mantri, M, et al.
Almmustuhtton: (2012)

Mechanistic studies on three 2-oxoglutarate-dependent oxygenases of flavonoid biosynthesis: anthocyanidin synthase, flavonol synthase, and flavanone 3beta-hydroxylase.
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Almmustuhtton: (2004)

A fluorescence-based assay for 2-oxoglutarate-dependent oxygenases.
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Almmustuhtton: (2005)

Identification of inhibitors for a family of human oxoglutarate-dependent oxygenases
Dahkki: Nowak, R
Almmustuhtton: (2015)

Interplay between 2-oxoglutarate oxygenases and cancer: studies on the aspartyl/asparaginyl-beta-hydroxylase
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Almmustuhtton: (2014)

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Almmustuhtton: (2008)

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Dahkki: Aik, WS
Almmustuhtton: (2014)

Mechanistic studies on 2-oxoglutarate dependent oxygenases
Dahkki: Szollossi, A
Almmustuhtton: (2012)

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Almmustuhtton: (2003)

Exploring links between 2-oxoglutarate-dependent oxygenases and Alzheimer's disease
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Almmustuhtton: (2022)

Structural studies on 2-oxoglutarate oxygenases and related double-stranded beta-helix fold proteins.
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Almmustuhtton: (2006)

Mechanistic studies on the application of DNA aptamers as inhibitors of 2-oxoglutarate-dependent oxygenases.
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Almmustuhtton: (2012)

Functional and inhibition studies on 2-oxoglutarate-dependent oxygenases
Dahkki: Thalhammer, A
Almmustuhtton: (2012)

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Almmustuhtton: (2010)

Crystal Structure of the 2-Oxoglutarate- and Fe(II)-Dependent Lysyl Hydroxylase JMJD6.
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Almmustuhtton: (2010)

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Almmustuhtton: (2003)

2-Oxoglutarate oxygenases are inhibited by a range of transition metals.
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Almmustuhtton: (2010)

PROLINE 4-HYDROXYLASE - STEREOCHEMICAL COURSE OF THE REACTION
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Almmustuhtton: (1993)

NMR studies on 2-oxoglutarate oxygenases
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Almmustuhtton: (2013)

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Almmustuhtton: (2009)

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Almmustuhtton: (2012)

The potential of 2-oxoglutarate oxygenases acting on nucleic acids as therapeutic targets
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Almmustuhtton: (2012)

Structural and stereoelectronic insights into oxygenase catalyzed formation of ethylene from 2-oxoglutarate
Dahkki: Zhang, Z, et al.
Almmustuhtton: (2017)

A photoreactive small-molecule probe for 2-oxoglutarate oxygenases.
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Almmustuhtton: (2011)

Studies on deacetoxycephalosporin C synthase support a consensus mechanism for 2-oxoglutarate dependent oxygenases.
Dahkki: Tarhonskaya, H, et al.
Almmustuhtton: (2014)

Physiological and biochemical aspects of hydroxylations and demethylations catalyzed by human 2-oxoglutarate oxygenases.
Dahkki: Loenarz, C, et al.
Almmustuhtton: (2011)

Reporter ligand NMR screening method for 2-oxoglutarate oxygenase inhibitors.
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Almmustuhtton: (2013)

Role of the jelly-roll fold in substrate binding by 2-oxoglutarate oxygenases.
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Almmustuhtton: (2012)

Fluorinated derivatives of pyridine-2,4-dicarboxylate are potent inhibitors of human 2-oxoglutarate dependent oxygenases
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Almmustuhtton: (2021)

Structural analysis of the 2-oxoglutarate binding site of the circadian rhythm linked oxygenase JMJD5
Dahkki: Islam, MS, et al.
Almmustuhtton: (2022)

Biochemical and structural investigations clarify the substrate selectivity of the 2-oxoglutarate oxygenase JMJD6.
Dahkki: Islam, MS, et al.
Almmustuhtton: (2019)

Structural analysis of the 2-oxoglutarate binding site of the circadian rhythm linked oxygenase JMJD5
Dahkki: Md. Saiful Islam, et al.
Almmustuhtton: (2022-11-01)

Roles of 2-oxoglutarate oxygenases and isopenicillin N synthase in ß-lactam biosynthesis
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Almmustuhtton: (2018)