Clinical trial results in context: comparison of baseline characteristics and outcomes of 38,510 RECOVERY trial participants versus a reference population of 346,271 people hospitalised with COVID-19 in England

Background: Randomised trials are essential to reliably assess medical interventions. Nevertheless, interpretation of such studies, particularly when considering absolute effects, is enhanced by understanding how the trial population may differ from the populations it aims to represent. Methods: We...

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Main Authors: Pessoa-Amorim, G, Goldacre, R, Crichton, C, Stevens, W, Nunn, M, King, A, Murray, D, Welsh, R, Pinches, H, Rees, A, Morris, EJA, Landray, MJ, Haynes, R, Horby, P, Wallendszus, K, Peto, L, Campbell, M, Harper, C, Mafham, M
Format: Journal article
Language:English
Published: BioMed Central 2024