Genome‐wide meta‐analysis identifies 3 novel loci associated with stroke

We conducted a European‐only and transancestral genome‐wide association meta‐analysis in 72,147 stroke patients and 823,869 controls using data from UK Biobank (UKB) and the MEGASTROKE consortium. We identified an exonic polymorphism in NOS3 (rs1799983, p.Glu298Asp; p = 2.2E‐8, odds ratio [OR] = 1.0...

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Hlavní autoři: Malik, R, Rannikmäe, K, Traylor, M, Georgakis, M, Sargurupremraj, M, Markus, H, Hopewell, J, Debette, S, Sudlow, C, Dichgans, M
Médium: Journal article
Jazyk:English
Vydáno: Wiley 2018