CD45 exclusion and crosslinking-based receptor signaling together broaden FcεRI reactivity
For many years, the high-affinity receptor for immunoglobulin E (IgE) FcεRI, which is expressed by mast cells and basophils, has been widely held to be the exemplar of cross linking (that is, aggregation-dependent) signaling receptors. We found, however, that FcεRI signaling could occur in the prese...
| Main Authors: | , , , , , , |
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| Format: | Journal article |
| Published: |
American Association for the Advancement of Science
2018
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