Correlation of ST-segment "hump sign" during exercise testing with impaired diastolic function of the left ventricle.
BACKGROUND: The appearance of a discrete upward deflection of the ST segment, termed the ST hump sign during exercise testing has been associated with resting hypertension and exaggerated blood pressure response to exercise. OBJECTIVE: We investigated the correlation between the presence of hump si...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
2010
|
| _version_ | 1826264780734726144 |
|---|---|
| author | Michaelides, A Raftopoulos, L Aggeli, C Liakos, C Antoniades, C Fourlas, C Stamatopoulos, E Ioakeimides, N Soulis, D Stefanadis, C |
| author_facet | Michaelides, A Raftopoulos, L Aggeli, C Liakos, C Antoniades, C Fourlas, C Stamatopoulos, E Ioakeimides, N Soulis, D Stefanadis, C |
| author_sort | Michaelides, A |
| collection | OXFORD |
| description | BACKGROUND: The appearance of a discrete upward deflection of the ST segment, termed the ST hump sign during exercise testing has been associated with resting hypertension and exaggerated blood pressure response to exercise. OBJECTIVE: We investigated the correlation between the presence of hump sign during exercise testing with coexisting impaired diastolic function of the left ventricle (LV) at these patients. METHODS: We formed a cohort of 237 nonconsecutive patients (140 males, 41 +/- 5 years old) having undergone a treadmill test, according to the Bruce protocol, which divided into 2 groups: group A, including 130 patients which presented ST-segment hump sign at any of the leads of the electrocardiograms recorded during exercise, and group B, including 107 patients that didn't. All patients subsequently underwent an echocardiographic estimation of the LV diastolic function, using conventional and Tissue Doppler Imaging techniques. RESULTS: From 237 patients included in our study, 106 had echocardiographic signs of diastolic LV dysfunction. Among them, the appearance of ST hump sign at the peak of exercise testing was observed in 93 patients (88%), particularly in the inferior and lateral leads, while no ST hump sign was observed only in 13 patients (12%) with impaired diastolic LV function. CONCLUSIONS: The appearance of ST segment hump sign during exercise testing is strongly correlated with diastolic LV dysfunction and can be used as an exercise electrocardiographic index of diastolic LV dysfunction, independently from the echocardiographic study. |
| first_indexed | 2024-03-06T20:13:21Z |
| format | Journal article |
| id | oxford-uuid:2b5576e0-9dbe-4532-84f3-ac09577a5c0a |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T20:13:21Z |
| publishDate | 2010 |
| record_format | dspace |
| spelling | oxford-uuid:2b5576e0-9dbe-4532-84f3-ac09577a5c0a2022-03-26T12:30:15ZCorrelation of ST-segment "hump sign" during exercise testing with impaired diastolic function of the left ventricle.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:2b5576e0-9dbe-4532-84f3-ac09577a5c0aEnglishSymplectic Elements at Oxford2010Michaelides, ARaftopoulos, LAggeli, CLiakos, CAntoniades, CFourlas, CStamatopoulos, EIoakeimides, NSoulis, DStefanadis, C BACKGROUND: The appearance of a discrete upward deflection of the ST segment, termed the ST hump sign during exercise testing has been associated with resting hypertension and exaggerated blood pressure response to exercise. OBJECTIVE: We investigated the correlation between the presence of hump sign during exercise testing with coexisting impaired diastolic function of the left ventricle (LV) at these patients. METHODS: We formed a cohort of 237 nonconsecutive patients (140 males, 41 +/- 5 years old) having undergone a treadmill test, according to the Bruce protocol, which divided into 2 groups: group A, including 130 patients which presented ST-segment hump sign at any of the leads of the electrocardiograms recorded during exercise, and group B, including 107 patients that didn't. All patients subsequently underwent an echocardiographic estimation of the LV diastolic function, using conventional and Tissue Doppler Imaging techniques. RESULTS: From 237 patients included in our study, 106 had echocardiographic signs of diastolic LV dysfunction. Among them, the appearance of ST hump sign at the peak of exercise testing was observed in 93 patients (88%), particularly in the inferior and lateral leads, while no ST hump sign was observed only in 13 patients (12%) with impaired diastolic LV function. CONCLUSIONS: The appearance of ST segment hump sign during exercise testing is strongly correlated with diastolic LV dysfunction and can be used as an exercise electrocardiographic index of diastolic LV dysfunction, independently from the echocardiographic study. |
| spellingShingle | Michaelides, A Raftopoulos, L Aggeli, C Liakos, C Antoniades, C Fourlas, C Stamatopoulos, E Ioakeimides, N Soulis, D Stefanadis, C Correlation of ST-segment "hump sign" during exercise testing with impaired diastolic function of the left ventricle. |
| title | Correlation of ST-segment "hump sign" during exercise testing with impaired diastolic function of the left ventricle. |
| title_full | Correlation of ST-segment "hump sign" during exercise testing with impaired diastolic function of the left ventricle. |
| title_fullStr | Correlation of ST-segment "hump sign" during exercise testing with impaired diastolic function of the left ventricle. |
| title_full_unstemmed | Correlation of ST-segment "hump sign" during exercise testing with impaired diastolic function of the left ventricle. |
| title_short | Correlation of ST-segment "hump sign" during exercise testing with impaired diastolic function of the left ventricle. |
| title_sort | correlation of st segment hump sign during exercise testing with impaired diastolic function of the left ventricle |
| work_keys_str_mv | AT michaelidesa correlationofstsegmenthumpsignduringexercisetestingwithimpaireddiastolicfunctionoftheleftventricle AT raftopoulosl correlationofstsegmenthumpsignduringexercisetestingwithimpaireddiastolicfunctionoftheleftventricle AT aggelic correlationofstsegmenthumpsignduringexercisetestingwithimpaireddiastolicfunctionoftheleftventricle AT liakosc correlationofstsegmenthumpsignduringexercisetestingwithimpaireddiastolicfunctionoftheleftventricle AT antoniadesc correlationofstsegmenthumpsignduringexercisetestingwithimpaireddiastolicfunctionoftheleftventricle AT fourlasc correlationofstsegmenthumpsignduringexercisetestingwithimpaireddiastolicfunctionoftheleftventricle AT stamatopoulose correlationofstsegmenthumpsignduringexercisetestingwithimpaireddiastolicfunctionoftheleftventricle AT ioakeimidesn correlationofstsegmenthumpsignduringexercisetestingwithimpaireddiastolicfunctionoftheleftventricle AT soulisd correlationofstsegmenthumpsignduringexercisetestingwithimpaireddiastolicfunctionoftheleftventricle AT stefanadisc correlationofstsegmenthumpsignduringexercisetestingwithimpaireddiastolicfunctionoftheleftventricle |