Tetrahydrobiopterin and alkylglycerol monooxygenase substantially alter the murine macrophage lipidome.
Tetrahydrobiopterin is a cofactor synthesized from GTP with well-known roles in enzymatic nitric oxide synthesis and aromatic amino acid hydroxylation. It is used to treat mild forms of phenylketonuria. Less is known about the role of tetrahydrobiopterin in lipid metabolism, although it is essential...
Main Authors: | Watschinger, K, Keller, M, McNeill, E, Alam, M, Lai, S, Sailer, S, Rauch, V, Patel, J, Hermetter, A, Golderer, G, Geley, S, Werner-Felmayer, G, Plumb, R, Astarita, G, Ralser, M, Channon, K, Werner, E |
---|---|
Format: | Journal article |
Language: | English |
Published: |
National Academy of Sciences
2015
|
Similar Items
-
Tetrahydrobiopterin in cardiovascular health and disease.
by: Bendall, J, et al.
Published: (2014) -
When the genome bluffs: a tandem duplication event during generation of a novel Agmo knockout mouse model fools routine genotyping
by: Sailer, S, et al.
Published: (2021) -
Mast cell tetrahydrobiopterin contributes to itch in mice
by: Zschiebsch, K, et al.
Published: (2018) -
The role of tetrahydrobiopterin in inflammation and cardiovascular disease.
by: McNeill, E, et al.
Published: (2012) -
A requirement for Gch1 and tetrahydrobiopterin in embryonic development.
by: Douglas, G, et al.
Published: (2015)