Tetrahydrobiopterin and alkylglycerol monooxygenase substantially alter the murine macrophage lipidome.

Tetrahydrobiopterin is a cofactor synthesized from GTP with well-known roles in enzymatic nitric oxide synthesis and aromatic amino acid hydroxylation. It is used to treat mild forms of phenylketonuria. Less is known about the role of tetrahydrobiopterin in lipid metabolism, although it is essential...

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Hlavní autoři: Watschinger, K, Keller, M, McNeill, E, Alam, M, Lai, S, Sailer, S, Rauch, V, Patel, J, Hermetter, A, Golderer, G, Geley, S, Werner-Felmayer, G, Plumb, R, Astarita, G, Ralser, M, Channon, K, Werner, E
Médium: Journal article
Jazyk:English
Vydáno: National Academy of Sciences 2015