FOXN1 deficient nude severe combined immunodeficiency
Nude severe combined immunodeficiency is a rare inherited disease caused by autosomal recessive loss-of-function mutations in FOXN1. This gene encodes a transcription factor essential for the development of the thymus, the primary lymphoid organ that supports T-cell development and selection. To dat...
Main Authors: | , |
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Format: | Journal article |
Language: | English |
Published: |
BioMed Central
2017
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