Complement factor I in health and disease.

Complement factor I in health and disease.

Factor I (FI) is a crucial inhibitor controlling all complement pathways due to its ability to degrade activated complement proteins C3b and C4b in the presence of cofactors such as factor H, C4b-binding protein, complement receptor 1 or CD46. Complete deficiency of FI, which is synthesized mainly i...

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Detalles Bibliográficos
Main Authors:	Nilsson, S, Sim, R, Lea, S, Fremeaux-Bacchi, V, Blom, A
Formato:	Journal article
Idioma:	English
Publicado:	2011

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