Complement factor I in health and disease.
Factor I (FI) is a crucial inhibitor controlling all complement pathways due to its ability to degrade activated complement proteins C3b and C4b in the presence of cofactors such as factor H, C4b-binding protein, complement receptor 1 or CD46. Complete deficiency of FI, which is synthesized mainly i...
| Main Authors: | , , , , |
|---|---|
| 格式: | Journal article |
| 语言: | English |
| 出版: |
2011
|