The ER membrane protein complex is a transmembrane domain insertase
Insertion of proteins into membranes is an essential cellular process. The extensive biophysical and topological diversity of membrane proteins necessitates multiple insertion pathways that remain incompletely defined. Here, we found that known membrane insertion pathways fail to effectively engage...
Main Authors: | Guna, A, Volkmar, N, Christianson, J, Hegde, R |
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Format: | Journal article |
Language: | English |
Published: |
American Association for the Advancement of Science
2017
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