SAP controls T cell responses to virus and terminal differentiation of TH2 cells.
SH2D1A, which encodes signaling lymphocyte activation molecule (SLAM)-associated protein (SAP), is altered in patients with X-linked lymphoproliferative disease (XLP), a primary immunodeficiency. SAP-deficient mice infected with lymphocytic choriomeningitis virus had greatly increased numbers of CD8...
Autors principals: | Wu, C, Nguyen, K, Pien, G, Wang, N, Gullo, C, Howie, D, Sosa, MR, Edwards, M, Borrow, P, Satoskar, A, Sharpe, A, Biron, C, Terhorst, C |
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Format: | Journal article |
Idioma: | English |
Publicat: |
2001
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