SMART 5: domains in the context of genomes and networks.
The Simple Modular Architecture Research Tool (SMART) is an online resource (http://smart.embl.de/) used for protein domain identification and the analysis of protein domain architectures. Many new features were implemented to make SMART more accessible to scientists from different fields. The new &...
Main Authors: | , , , , , |
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Format: | Journal article |
Language: | English |
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2006
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_version_ | 1797060333811007488 |
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author | Letunic, I Copley, R Pils, B Pinkert, S Schultz, J Bork, P |
author_facet | Letunic, I Copley, R Pils, B Pinkert, S Schultz, J Bork, P |
author_sort | Letunic, I |
collection | OXFORD |
description | The Simple Modular Architecture Research Tool (SMART) is an online resource (http://smart.embl.de/) used for protein domain identification and the analysis of protein domain architectures. Many new features were implemented to make SMART more accessible to scientists from different fields. The new 'Genomic' mode in SMART makes it easy to analyze domain architectures in completely sequenced genomes. Domain annotation has been updated with a detailed taxonomic breakdown and a prediction of the catalytic activity for 50 SMART domains is now available, based on the presence of essential amino acids. Furthermore, intrinsically disordered protein regions can be identified and displayed. The network context is now displayed in the results page for more than 350 000 proteins, enabling easy analyses of domain interactions. |
first_indexed | 2024-03-06T20:15:40Z |
format | Journal article |
id | oxford-uuid:2c12ec1c-62de-4b91-b835-4e68c2b1080b |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-06T20:15:40Z |
publishDate | 2006 |
record_format | dspace |
spelling | oxford-uuid:2c12ec1c-62de-4b91-b835-4e68c2b1080b2022-03-26T12:34:42ZSMART 5: domains in the context of genomes and networks.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:2c12ec1c-62de-4b91-b835-4e68c2b1080bEnglishSymplectic Elements at Oxford2006Letunic, ICopley, RPils, BPinkert, SSchultz, JBork, PThe Simple Modular Architecture Research Tool (SMART) is an online resource (http://smart.embl.de/) used for protein domain identification and the analysis of protein domain architectures. Many new features were implemented to make SMART more accessible to scientists from different fields. The new 'Genomic' mode in SMART makes it easy to analyze domain architectures in completely sequenced genomes. Domain annotation has been updated with a detailed taxonomic breakdown and a prediction of the catalytic activity for 50 SMART domains is now available, based on the presence of essential amino acids. Furthermore, intrinsically disordered protein regions can be identified and displayed. The network context is now displayed in the results page for more than 350 000 proteins, enabling easy analyses of domain interactions. |
spellingShingle | Letunic, I Copley, R Pils, B Pinkert, S Schultz, J Bork, P SMART 5: domains in the context of genomes and networks. |
title | SMART 5: domains in the context of genomes and networks. |
title_full | SMART 5: domains in the context of genomes and networks. |
title_fullStr | SMART 5: domains in the context of genomes and networks. |
title_full_unstemmed | SMART 5: domains in the context of genomes and networks. |
title_short | SMART 5: domains in the context of genomes and networks. |
title_sort | smart 5 domains in the context of genomes and networks |
work_keys_str_mv | AT letunici smart5domainsinthecontextofgenomesandnetworks AT copleyr smart5domainsinthecontextofgenomesandnetworks AT pilsb smart5domainsinthecontextofgenomesandnetworks AT pinkerts smart5domainsinthecontextofgenomesandnetworks AT schultzj smart5domainsinthecontextofgenomesandnetworks AT borkp smart5domainsinthecontextofgenomesandnetworks |