Investigating D-lysine stereochemistry for epigenetic methylation, demethylation and recognition

Investigating D-lysine stereochemistry for epigenetic methylation, demethylation and recognition

Histone lysine methylation is regulated by Nε-methyltransferases, demethylases, and Nε-methyl lysine binding proteins. Thermodynamic, catalytic and computational studies were carried out to investigate the interaction of three epigenetic protein classes with synthetic histone substrates containing l...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Belle, R, Al Temimi, A, Kumar, K, Pieters, B, Tumber, A, Dunford, J, Johansson, C, Oppermann, U, Brown, T, Schofield, C, Hopkinson, R, Paton, R, Kawamura, A, Mecinović, J
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	Royal Society of Chemistry 2017

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