Investigating D-lysine stereochemistry for epigenetic methylation, demethylation and recognition

Investigating D-lysine stereochemistry for epigenetic methylation, demethylation and recognition

Histone lysine methylation is regulated by Nε-methyltransferases, demethylases, and Nε-methyl lysine binding proteins. Thermodynamic, catalytic and computational studies were carried out to investigate the interaction of three epigenetic protein classes with synthetic histone substrates containing l...

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Príomhchruthaitheoirí:	Belle, R, Al Temimi, A, Kumar, K, Pieters, B, Tumber, A, Dunford, J, Johansson, C, Oppermann, U, Brown, T, Schofield, C, Hopkinson, R, Paton, R, Kawamura, A, Mecinović, J
Formáid:	Journal article
Teanga:	English
Foilsithe / Cruthaithe:	Royal Society of Chemistry 2017

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