HLA DR4 is a marker for rapid disease progression in primary sclerosing cholangitis.
BACKGROUND/AIMS: Primary sclerosing cholangitis (PSC) is an inflammatory disease of the biliary tree associated with an increase in the HLA alleles DR3, DR52a, DR2, Dw2, and a decrease in DR4. However, it is not certain which of these alleles provides the primary associations. Our aim was to establi...
Main Authors: | Mehal, W, Lo, Y, Wordsworth, B, Neuberger, J, Hubscher, S, Fleming, K, Chapman, R |
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Format: | Journal article |
Language: | English |
Published: |
1994
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