Genetic deficiency of indoleamine 2,3-dioxygenase aggravates vascular but not liver disease in a nonalcoholic steatohepatitis and atherosclerosis comorbidity model

Genetic deficiency of indoleamine 2,3-dioxygenase aggravates vascular but not liver disease in a nonalcoholic steatohepatitis and atherosclerosis comorbidity model

<p>Nonalcoholic steatohepatitis (NASH) is a chronic liver disease that increases cardiovascular disease risk. Indoleamine 2,3-dioxygenase-1 (IDO1)-mediated tryptophan (Trp) metabolism has been proposed to play an immunomodulatory role in several diseases. The potential of IDO1 to be a link bet...

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Bibliographic Details
Main Authors:	Arora, A, Tripodi, GL, Kareinen, I, Berg, M, Forteza, MJ, Gisterå, A, Griepke, S, Casagrande, FB, Martins, JO, Abdalla, DSP, Cole, J, Monaco, C, Ketelhuth, DFJ
Format:	Journal article
Language:	English
Published:	MDPI 2022

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