Cerebellar ataxia in non-paraneoplastic Lambert-Eaton myasthenic syndrome.
Lambert-Eaton myasthenic syndrome (LEMS) is an immune-mediated disorder of the neuromuscular junction that rarely is associated with cerebellar ataxia (CA). We describe two patients with non-paraneoplastic LEMS associated with CA who showed high levels of anti-P/Q-type voltage-gated calcium channels...
| Main Authors: | , , , , , , |
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| Format: | Journal article |
| Language: | English |
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2008
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| _version_ | 1826264948587626496 |
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| author | Lorenzoni, P Scola, R Lang, B Kay, C Teive, H Kowacs, P Werneck, L |
| author_facet | Lorenzoni, P Scola, R Lang, B Kay, C Teive, H Kowacs, P Werneck, L |
| author_sort | Lorenzoni, P |
| collection | OXFORD |
| description | Lambert-Eaton myasthenic syndrome (LEMS) is an immune-mediated disorder of the neuromuscular junction that rarely is associated with cerebellar ataxia (CA). We describe two patients with non-paraneoplastic LEMS associated with CA who showed high levels of anti-P/Q-type voltage-gated calcium channels antibodies in the serum and cerebrospinal fluid, and reduced CMAP with increment after brief maximum voluntary contraction in electrophysiological studies. We suggest that LEMS should be considered in the differential diagnosis of patients with CA. |
| first_indexed | 2024-03-06T20:15:59Z |
| format | Journal article |
| id | oxford-uuid:2c28460a-c692-49fb-83f2-e6cfc4407647 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T20:15:59Z |
| publishDate | 2008 |
| record_format | dspace |
| spelling | oxford-uuid:2c28460a-c692-49fb-83f2-e6cfc44076472022-03-26T12:35:18ZCerebellar ataxia in non-paraneoplastic Lambert-Eaton myasthenic syndrome.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:2c28460a-c692-49fb-83f2-e6cfc4407647EnglishSymplectic Elements at Oxford2008Lorenzoni, PScola, RLang, BKay, CTeive, HKowacs, PWerneck, LLambert-Eaton myasthenic syndrome (LEMS) is an immune-mediated disorder of the neuromuscular junction that rarely is associated with cerebellar ataxia (CA). We describe two patients with non-paraneoplastic LEMS associated with CA who showed high levels of anti-P/Q-type voltage-gated calcium channels antibodies in the serum and cerebrospinal fluid, and reduced CMAP with increment after brief maximum voluntary contraction in electrophysiological studies. We suggest that LEMS should be considered in the differential diagnosis of patients with CA. |
| spellingShingle | Lorenzoni, P Scola, R Lang, B Kay, C Teive, H Kowacs, P Werneck, L Cerebellar ataxia in non-paraneoplastic Lambert-Eaton myasthenic syndrome. |
| title | Cerebellar ataxia in non-paraneoplastic Lambert-Eaton myasthenic syndrome. |
| title_full | Cerebellar ataxia in non-paraneoplastic Lambert-Eaton myasthenic syndrome. |
| title_fullStr | Cerebellar ataxia in non-paraneoplastic Lambert-Eaton myasthenic syndrome. |
| title_full_unstemmed | Cerebellar ataxia in non-paraneoplastic Lambert-Eaton myasthenic syndrome. |
| title_short | Cerebellar ataxia in non-paraneoplastic Lambert-Eaton myasthenic syndrome. |
| title_sort | cerebellar ataxia in non paraneoplastic lambert eaton myasthenic syndrome |
| work_keys_str_mv | AT lorenzonip cerebellarataxiainnonparaneoplasticlamberteatonmyasthenicsyndrome AT scolar cerebellarataxiainnonparaneoplasticlamberteatonmyasthenicsyndrome AT langb cerebellarataxiainnonparaneoplasticlamberteatonmyasthenicsyndrome AT kayc cerebellarataxiainnonparaneoplasticlamberteatonmyasthenicsyndrome AT teiveh cerebellarataxiainnonparaneoplasticlamberteatonmyasthenicsyndrome AT kowacsp cerebellarataxiainnonparaneoplasticlamberteatonmyasthenicsyndrome AT werneckl cerebellarataxiainnonparaneoplasticlamberteatonmyasthenicsyndrome |