Genome-wide association studies of brain imaging phenotypes in UK Biobank

Genome-wide association studies of brain imaging phenotypes in UK Biobank

The genetic architecture of brain structure and function is largely unknown. To investigate this, we carried out genomewide association studies of 3,144 functional and structural brain imaging phenotypes from UK Biobank (discovery data set 8,428 subjects). Here we show that many of these phenotypes...

Descrizione completa

Dettagli Bibliografici
Autori principali:	Elliott, L, Sharp, K, Alfaro-Almagro, F, Shi, S, Miller, K, Douaud, G, Marchini, J, Smith, S
Natura:	Journal article
Pubblicazione:	Nature Research 2018

Documenti analoghi

An expanded set of genome-wide association studies of brain imaging phenotypes in UK Biobank
di: Smith, SM, et al.
Pubblicazione: (2021)

The genetic basis of human brain structure and function: 1,262 genome-wide associations found from 3,144 GWAS of multimodal brain imaging phenotypes from 9,707 UK Biobank participants
di: Elliott, L, et al.
Pubblicazione: (2017)

Phenotypic and genetic associations of quantitative magnetic susceptibility in UK Biobank brain imaging
di: Wang, C, et al.
Pubblicazione: (2022)

Brain imaging in UK Biobank
di: Alfaro-Almagro, F
Pubblicazione: (2020)

Telomere length and brain imaging phenotypes in UK Biobank
di: Topiwala, A, et al.
Pubblicazione: (2023)

Telomere length and brain imaging phenotypes in UK Biobank
di: Anya Topiwala, et al.
Pubblicazione: (2023-01-01)

Telomere length and brain imaging phenotypes in UK Biobank.
di: Anya Topiwala, et al.
Pubblicazione: (2023-01-01)

Confound modelling in UK Biobank brain imaging
di: Alfaro-Almagro, F, et al.
Pubblicazione: (2020)

Confound modelling in UK Biobank brain imaging
di: Fidel Alfaro-Almagro, et al.
Pubblicazione: (2021-01-01)

The UK Biobank resource with deep phenotyping and genomic data
di: Bycroft, C, et al.
Pubblicazione: (2018)

Multimodal population brain imaging in the UK Biobank prospective epidemiological study
di: Miller, K, et al.
Pubblicazione: (2016)

Internally-consistent and fully-unbiased multimodal MRI brain template construction from UK Biobank: Oxford-MM
di: Arthofer, C, et al.
Pubblicazione: (2024)

Image Processing and Quality Control for the first 10,000 Brain Imaging Datasets from UK Biobank
di: Alfaro Almagro, F, et al.
Pubblicazione: (2017)

Image processing and quality control for the first 10,000 brain imaging datasets from UK Biobank
di: Alfaro-Almagro, F, et al.
Pubblicazione: (2017)

SARS-CoV-2 is associated with changes in brain structure in UK Biobank
di: Douaud, G, et al.
Pubblicazione: (2022)

Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways
di: David M. Howard, et al.
Pubblicazione: (2018-04-01)

Adapting UK Biobank imaging for use in a routine memory clinic setting: The Oxford Brain Health Clinic
di: Griffanti, L, et al.
Pubblicazione: (2022)

Phenotypic and genetic associations between anhedonia and brain structure in UK Biobank
di: Xingxing Zhu, et al.
Pubblicazione: (2021-07-01)

Genome-wide association study of multisite chronic pain in UK Biobank.
di: Keira J A Johnston, et al.
Pubblicazione: (2019-06-01)

Addendum: Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways
di: David M. Howard, et al.
Pubblicazione: (2018-08-01)

Adapting UK Biobank imaging for use in a routine memory clinic setting: The Oxford Brain Health Clinic
di: Ludovica Griffanti, et al.
Pubblicazione: (2022-01-01)

Author Correction: Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways
di: David M. Howard, et al.
Pubblicazione: (2021-03-01)

Reproducibility in the UK biobank of genome-wide significant signals discovered in earlier genome-wide association studies
di: Jack W. O’Sullivan, et al.
Pubblicazione: (2021-09-01)

Sex-stratified genome-wide association study of multisite chronic pain in UK Biobank.
di: Keira J A Johnston, et al.
Pubblicazione: (2021-04-01)

Exome-wide evidence of compound heterozygous effects across common phenotypes in the UK Biobank
di: Lassen, FH, et al.
Pubblicazione: (2024)

Genome-wide study of hair colour in UK Biobank explains most of the SNP heritability
di: Morgan, MD, et al.
Pubblicazione: (2018)

Adapting the UK Biobank brain imaging protocol and analysis pipeline for the C-MORE multi-organ study of COVID-19 survivors
di: Griffanti, L, et al.
Pubblicazione: (2021)

Association between cannabis use and brain imaging phenotypes in UK Biobank: an observational and Mendelian randomization study
di: Ishrat, S, et al.
Pubblicazione: (2023)

The Associations of Bone Health with Cardiovascular Disease and Imaging Phenotypes in the UK Biobank
di: Dorina Condurache, MBBS, et al.
Pubblicazione: (2024-01-01)

Phenome-wide heritability analysis of the UK Biobank
di: Ge, Tian, et al.
Pubblicazione: (2017)

Phenome-wide heritability analysis of the UK Biobank.
di: Tian Ge, et al.
Pubblicazione: (2017-04-01)

Asthma exacerbations and eosinophilia in the UK Biobank: a genome-wide association study
di: Ahmed Edris, et al.
Pubblicazione: (2024-01-01)

Genome-wide association of polygenic risk extremes for Alzheimer's disease in the UK Biobank
di: Catarina Gouveia, et al.
Pubblicazione: (2022-05-01)

Genome-wide association study of medication-use and associated disease in the UK Biobank
di: Yeda Wu, et al.
Pubblicazione: (2019-04-01)

Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data
di: Zeggini, E, et al.
Pubblicazione: (2019)

A tissue-level phenome-wide network map of colocalized genes and phenotypes in the UK Biobank
di: Ghislain Rocheleau, et al.
Pubblicazione: (2022-08-01)

Estimation of brain age delta from brain imaging.
di: Smith, S, et al.
Pubblicazione: (2019)

Reliability of multi-site UK Biobank MRI brain phenotypes for the assessment of neuropsychiatric complications of SARS-CoV-2 infection: The COVID-CNS travelling heads study
di: Eugene Duff, et al.
Pubblicazione: (2022-01-01)

Hippocampal volume across age: Nomograms derived from over 19,700 people in UK Biobank
di: Nobis, L, et al.
Pubblicazione: (2019)

Genome-wide study of hair colour in UK Biobank explains most of the SNP heritability
di: Michael D. Morgan, et al.
Pubblicazione: (2018-12-01)