Reconstitution of antigen presentation in HLA class I-negative cancer cells with peptide-beta2m fusion molecules.

Reconstitution of antigen presentation in HLA class I-negative cancer cells with peptide-beta2m fusion molecules.

Engineered MHC-peptide targets capable of inducing recognition by CTL may prove useful in designing vaccines for infectious disease and cancer. We tested whether peptides directly linked to beta2-microglobulin (beta2m) could complex with human HLA class I heavy chain, and could be recognized by huma...

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Bibliographic Details
Main Authors:	Tafuro, S, Meier, U, Dunbar, P, Jones, E, Layton, G, Hunter, MG, Bell, J, Mcmichael, A
Format:	Journal article
Language:	English
Published:	2001

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