Multi-factor dimensionality reduction applied to a large prospective investigation on gene-gene and gene-environment interactions.

Multi-factor dimensionality reduction applied to a large prospective investigation on gene-gene and gene-environment interactions.

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It is becoming increasingly evident that single-locus effects cannot explain complex multifactorial human diseases like cancer. We applied the multi-factor dimensionality reduction (MDR) method to a large cohort study on gene-environment and gene-gene interactions. The study (case-control nested in...

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Bibliographic Details
Main Authors: Manuguerra, M, Matullo, G, Veglia, F, Autrup, H, Dunning, A, Garte, S, Gormally, E, Malaveille, C, Guarrera, S, Polidoro, S, Saletta, F, Peluso, M, Airoldi, L, Overvad, K, Raaschou-Nielsen, O, Clavel-Chapelon, F, Linseisen, J, Boeing, H, Trichopoulos, D, Kalandidi, A, Palli, D, Krogh, V, Tumino, R, Panico, S, Bueno-De-Mesquita, H
Format: Journal article
Language:English
Published: 2007

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