Yeast artificial chromosomes: an alternative approach to the molecular analysis of mouse developmental mutations.
Mammalian genetics now allows a molecular study of genomic regions previously analysed by genetic and embryological techniques. To simplify such an analysis, we have established a number of libraries of mouse DNA in Yeast Artificial Chromosome (YAC) vectors, constructed either by partial digestion w...
Main Authors: | Larin, Z, Lehrach, H |
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Format: | Journal article |
Language: | English |
Published: |
1990
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