Yeast artificial chromosomes: an alternative approach to the molecular analysis of mouse developmental mutations.

Mammalian genetics now allows a molecular study of genomic regions previously analysed by genetic and embryological techniques. To simplify such an analysis, we have established a number of libraries of mouse DNA in Yeast Artificial Chromosome (YAC) vectors, constructed either by partial digestion w...

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Autori principali: Larin, Z, Lehrach, H
Natura: Journal article
Lingua:English
Pubblicazione: 1990