Peripheral blood monocyte-to-lymphocyte ratio at study enrollment predicts efficacy of the RTS,S malaria vaccine: analysis of pooled phase II clinical trial data.

Peripheral blood monocyte-to-lymphocyte ratio at study enrollment predicts efficacy of the RTS,S malaria vaccine: analysis of pooled phase II clinical trial data.

BACKGROUND: RTS,S is the most advanced candidate malaria vaccine but it is only partially protective and the causes of inter-individual variation in efficacy are poorly understood. Here, we investigated whether peripheral blood monocyte-to-lymphocyte ratios (ML ratio), previously shown to correlate...

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Dettagli Bibliografici
Autori principali:	Warimwe, G, Fletcher, H, Olotu, A, Agnandji, S, Hill, A, Marsh, K, Bejon, P
Natura:	Journal article
Lingua:	English
Pubblicazione:	BioMed Central 2013

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