Microevolution of Burkholderia pseudomallei during an acute infection.
We used whole-genome sequencing to evaluate 69 independent colonies of Burkholderia pseudomallei isolated from seven body sites of a patient with acute disseminated melioidosis. Fourteen closely related genotypes were found, providing evidence for the rapid in vivo diversification of B. pseudomallei...
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| Main Authors: |
Limmathurotsakul, D,
Holden, M,
Coupland, P,
Price, E,
Chantratita, N,
Wuthiekanun, V,
Amornchai, P,
Parkhill, J,
Peacock, S |
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| 格式: | Journal article
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| 语言: | English |
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| 出版: |
American Society for Microbiology
2014
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