Probing the effect of temperature on the backbone dynamics of the human alpha-lactalbumin molten globule.
Molten globules are compact, partially folded proteins postulated to be general intermediates in protein folding. Human alpha-lactalbumin (alpha-LA) is a two-domain Ca(2+)-binding protein that partially unfolds at low pH to form a molten globule. NMR spectra of molten globules are characterized by b...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2008
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