Neuroprotection by dimethyloxalylglycine following permanent and transient focal cerebral ischemia in rats.

Neuroprotection by dimethyloxalylglycine following permanent and transient focal cerebral ischemia in rats.

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Dimethyloxalylglycine (DMOG) is an inhibitor of prolyl-4-hydroxylase domain (PHD) enzymes that regulate the stability of hypoxia-inducible factor (HIF). We investigated the effect of DMOG on the outcome after permanent and transient middle cerebral artery occlusion (p/tMCAO) in the rat. Before and a...

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Bibliographic Details
Main Authors:	Nagel, S, Papadakis, M, Chen, R, Hoyte, L, Brooks, K, Gallichan, D, Sibson, N, Pugh, C, Buchan, A
Format:	Journal article
Language:	English
Published:	2011

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