Structural motifs involved in human IgG antibody effector functions.
A humanized IgG antibody to CAMPATH-1 antigen (CDw52) is known to be lympholytic both in vitro and in vivo. So as to improve therapeutic potency through protein engineering strategies, we wish to define the structural motifs underlying some of the documented differences in function between human (h)...
Main Authors: | Greenwood, J, Clark, M, Waldmann, H |
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Format: | Journal article |
Language: | English |
Published: |
1993
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