Lithiation-electrophilic substitution of N-thiopivaloylazetidine.
The fourth protocol: the rarely studied N-thiopivaloyl group plays a crucial role in mediating efficient α lithiation and incorporation of diverse electrophiles onto an azetidine ring; in the presence of chiral ligands, this chemistry also provides the first example of an enantioselective electrophi...
Main Authors: | Hodgson, D, Kloesges, J |
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Format: | Journal article |
Language: | English |
Published: |
2010
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