Role of the jelly-roll fold in substrate binding by 2-oxoglutarate oxygenases.

2-Oxoglutarate (2OG) and ferrous iron dependent oxygenases catalyze two-electron oxidations of a range of small and large molecule substrates, including proteins/peptides/amino acids, nucleic acids/bases, and lipids, as well as natural products including antibiotics and signaling molecules. 2OG oxyg...

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Detalles Bibliográficos
Autores principales: Aik, W, McDonough, M, Thalhammer, A, Chowdhury, R, Schofield, C
Formato: Journal article
Lenguaje:English
Publicado: 2012