Role of the jelly-roll fold in substrate binding by 2-oxoglutarate oxygenases.

2-Oxoglutarate (2OG) and ferrous iron dependent oxygenases catalyze two-electron oxidations of a range of small and large molecule substrates, including proteins/peptides/amino acids, nucleic acids/bases, and lipids, as well as natural products including antibiotics and signaling molecules. 2OG oxyg...

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Main Authors: Aik, W, McDonough, M, Thalhammer, A, Chowdhury, R, Schofield, C
格式: Journal article
语言:English
出版: 2012