JmjC catalysed histone H2a N -methyl arginine demethylation and C4-arginine hydroxylation reveals importance of sequence-reactivity relationships
2-Oxoglutarate (2OG) dependent Nε-methyl lysine demethylases (JmjC-KDMs) regulate eukaryotic transcription. We report studies showing that isolated forms of all human KDM4 and KDM5 JmjC enzymes catalyse demethylation of N-methylated Arg-3 of histone H2a. Unexpectedly, the results reveal that KDM4E a...
Հիմնական հեղինակներ: | Bonnici, J, Oueini, R, Salah, E, Johansson, C, Pires, E, Abboud, M, Dawber, RS, Tumber, A, Rabe, P, Saraç, H, Schofield, CJ, Kawamura, A |
---|---|
Ձևաչափ: | Journal article |
Լեզու: | English |
Հրապարակվել է: |
Nature Research
2024
|
Նմանատիպ նյութեր
-
JmjC catalysed histone H2a N-methyl arginine demethylation and C4-arginine hydroxylation reveals importance of sequence-reactivity relationships
: Joanna Bonnici, և այլն
Հրապարակվել է: (2024-11-01) -
The catalytic domains of all human KDM5 JmjC demethylases catalyse N-methyl arginine demethylation.
: Bonnici, J, և այլն
Հրապարակվել է: (2023) -
Arginine demethylation is catalysed by a subset of JmjC histone lysine demethylases.
: Walport, L, և այլն
Հրապարակվել է: (2016) -
Arginine demethylation is catalysed by a subset of JmjC histone lysine demethylases
: Louise J. Walport, և այլն
Հրապարակվել է: (2016-06-01) -
JmjC catalysed histone H2a N-methyl arginine demethylation and C4-arginine hydroxylation reveals importance of sequence-reactivity relationships
: Bonnici, J
Հրապարակվել է: (2024)