A network aggregation model for amyloid-β dynamics and treatment of Alzheimer’s diseases at the brain scale

Neurodegenerative diseases are associated with the assembly of specific proteins into oligomers and fibrillar aggregates. At the brain scale, these protein assemblies can diffuse through the brain and seed other regions, creating an autocatalytic protein progression. The growth and transport of thes...

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Bibliographic Details
Main Authors: Brennan, GS, Goriely, A
Format: Journal article
Language:English
Published: Springer 2025