Interleukin-18 is a novel mitogen of osteogenic and chondrogenic cells.

IL-18 was identified due to its ability to induce interferon-gamma (IFNgamma) production by T cells. It is a pleiotropic factor that shares structural features with IL-1 and functional activities with IL-12. IL-18 has a role in T cell development, where it has been demonstrated to act cooperatively...

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Detalhes bibliográficos
Principais autores: Cornish, J, Gillespie, M, Callon, K, Horwood, N, Moseley, J, Reid, I
Formato: Journal article
Idioma:English
Publicado em: 2003