MIG (CXCL9) is a more sensitive measure than IFN-gamma of vaccine induced T-cell responses in volunteers receiving investigated malaria vaccines.
For many years the IFN-gamma ex vivo ELISPOT has been a major assay for assessing human T-cell responses generated by malaria vaccines. The ELISPOT assay is a sensitive assay, but an imperfect correlate of protection against malaria. Monokine induced by gamma (MIG), or CXCL9, is a chemokine induced...
Main Authors: | Berthoud, T, Dunachie, S, Todryk, S, Hill, A, Fletcher, H |
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Format: | Journal article |
Language: | English |
Published: |
2009
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