Structural insights into hedgehog ligand sequestration by the human hedgehog-interacting protein HHIP.

Hedgehog (Hh) morphogens have fundamental roles in development, whereas dysregulation of Hh signaling leads to disease. Multiple cell-surface receptors are responsible for transducing and/or regulating Hh signals. Among these, the Hedgehog-interacting protein (Hhip) is a highly conserved, vertebrate...

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Váldodahkkit: Bishop, B, Aricescu, A, Harlos, K, O'Callaghan, C, Jones, E, Siebold, C
Materiálatiipa: Journal article
Giella:English
Almmustuhtton: 2009