Overexpressing centriole-replication proteins in vivo induces centriole overduplication and de novo formation.

BACKGROUND: Centrosomes have important roles in many aspects of cell organization, and aberrations in their number and function are associated with various diseases, including cancer. Centrosomes consist of a pair of centrioles surrounded by a pericentriolar matrix (PCM), and their replication is t...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính: Peel, N, Stevens, N, Basto, R, Raff, J
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2007

Những quyển sách tương tự