Carotid artery stenting in patients with acute coronary syndrome: a possible primary therapy for symptomatic carotid stenosis

PURPOSE: To report the results of carotid artery stenting (CAS) in symptomatic patients (stroke/transient ischemic attack) after recent percutaneous transluminal coronary angioplasty (PTCA) for acute coronary syndrome (ACS). METHODS: Between January 2009 and July 2011, 28 consecutive patients (18 w...

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Main Authors: Casana, R, Halliday, A, Bianchi, P, Fresa, E, Silani, V, Parati, G, Blengino, S, Cireni, L, Adobbati, L, Calvillo, L, Tolva, V
Format: Journal article
Language:English
Published: Sage Publications 2013
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author Casana, R
Halliday, A
Bianchi, P
Fresa, E
Silani, V
Parati, G
Blengino, S
Cireni, L
Adobbati, L
Calvillo, L
Tolva, V
author_facet Casana, R
Halliday, A
Bianchi, P
Fresa, E
Silani, V
Parati, G
Blengino, S
Cireni, L
Adobbati, L
Calvillo, L
Tolva, V
author_sort Casana, R
collection OXFORD
description PURPOSE: To report the results of carotid artery stenting (CAS) in symptomatic patients (stroke/transient ischemic attack) after recent percutaneous transluminal coronary angioplasty (PTCA) for acute coronary syndrome (ACS). METHODS: Between January 2009 and July 2011, 28 consecutive patients (18 women; mean age 66 years, range 42-82) underwent protected CAS for symptomatic carotid stenosis following recent PTCA that included bare or drug-eluting stents requiring uninterrupted dual antiplatelet therapy. Primary technical success, neurological complications, major adverse cardiovascular events, and death were evaluated at 30 days and over midterm follow-up. RESULTS: Technical success was 96%; 1 patient suffered a nonfatal major stroke (3.5% 30-day stroke rate) during the procedure. During a median 21.6-month follow-up, 4 (14%) patients died of myocardial infarction (all diabetic smokers with ejection fractions <40%), but there were no new neurological events. Estimated survival was 89.3% at 2 years. Further coronary interventions were performed in 2 diabetic patients with a body mass index >34 kg/m(2). CONCLUSION: This preliminary experience demonstrated that CAS is a reasonable, safe, and effective treatment for patients with symptomatic carotid artery stenosis who were recently treated with coronary stents requiring uninterrupted dual antiplatelet therapy.
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spelling oxford-uuid:2d93f234-4f5c-4653-b170-f9863a82eb302022-03-26T12:43:49ZCarotid artery stenting in patients with acute coronary syndrome: a possible primary therapy for symptomatic carotid stenosisJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:2d93f234-4f5c-4653-b170-f9863a82eb30EnglishSymplectic Elements at OxfordSage Publications2013Casana, RHalliday, ABianchi, PFresa, ESilani, VParati, GBlengino, SCireni, LAdobbati, LCalvillo, LTolva, V PURPOSE: To report the results of carotid artery stenting (CAS) in symptomatic patients (stroke/transient ischemic attack) after recent percutaneous transluminal coronary angioplasty (PTCA) for acute coronary syndrome (ACS). METHODS: Between January 2009 and July 2011, 28 consecutive patients (18 women; mean age 66 years, range 42-82) underwent protected CAS for symptomatic carotid stenosis following recent PTCA that included bare or drug-eluting stents requiring uninterrupted dual antiplatelet therapy. Primary technical success, neurological complications, major adverse cardiovascular events, and death were evaluated at 30 days and over midterm follow-up. RESULTS: Technical success was 96%; 1 patient suffered a nonfatal major stroke (3.5% 30-day stroke rate) during the procedure. During a median 21.6-month follow-up, 4 (14%) patients died of myocardial infarction (all diabetic smokers with ejection fractions <40%), but there were no new neurological events. Estimated survival was 89.3% at 2 years. Further coronary interventions were performed in 2 diabetic patients with a body mass index >34 kg/m(2). CONCLUSION: This preliminary experience demonstrated that CAS is a reasonable, safe, and effective treatment for patients with symptomatic carotid artery stenosis who were recently treated with coronary stents requiring uninterrupted dual antiplatelet therapy.
spellingShingle Casana, R
Halliday, A
Bianchi, P
Fresa, E
Silani, V
Parati, G
Blengino, S
Cireni, L
Adobbati, L
Calvillo, L
Tolva, V
Carotid artery stenting in patients with acute coronary syndrome: a possible primary therapy for symptomatic carotid stenosis
title Carotid artery stenting in patients with acute coronary syndrome: a possible primary therapy for symptomatic carotid stenosis
title_full Carotid artery stenting in patients with acute coronary syndrome: a possible primary therapy for symptomatic carotid stenosis
title_fullStr Carotid artery stenting in patients with acute coronary syndrome: a possible primary therapy for symptomatic carotid stenosis
title_full_unstemmed Carotid artery stenting in patients with acute coronary syndrome: a possible primary therapy for symptomatic carotid stenosis
title_short Carotid artery stenting in patients with acute coronary syndrome: a possible primary therapy for symptomatic carotid stenosis
title_sort carotid artery stenting in patients with acute coronary syndrome a possible primary therapy for symptomatic carotid stenosis
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