Induction of bystander T cell proliferation by viruses and type I interferon in vivo.
T cell proliferation in vivo is presumed to reflect a T cell receptor (TCR)-mediated polyclonal response directed to various environmental antigens. However, the massive proliferation of T cells seen in viral infections is suggestive of a bystander reaction driven by cytokines instead of the TCR. In...
Main Authors: | Tough, D, Borrow, P, Sprent, J |
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Format: | Journal article |
Language: | English |
Published: |
1996
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