Induction of bystander T cell proliferation by viruses and type I interferon in vivo.

T cell proliferation in vivo is presumed to reflect a T cell receptor (TCR)-mediated polyclonal response directed to various environmental antigens. However, the massive proliferation of T cells seen in viral infections is suggestive of a bystander reaction driven by cytokines instead of the TCR. In...

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Bibliographic Details
Main Authors: Tough, D, Borrow, P, Sprent, J
Format: Journal article
Language:English
Published: 1996

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