Crystal Structures of the p21-activated kinases PAK4, PAK5, and PAK6 reveal catalytic domain plasticity of active group II PAKs
p21-activated kinases have been classified into two groups based on their domain architecture. Group II PAKs (PAK4-6) regulate a wide variety of cellular functions, and PAK deregulation has been linked to tumor development. Structural comparison of five high-resolution structures comprising all acti...
主要な著者: | , , , , , , , , |
---|---|
フォーマット: | Journal article |
言語: | English |
出版事項: |
Cell Press
2007
|
主題: |