Scavenger receptors in innate immunity.
Scavenger receptors (SR) are expressed by myeloid cells (macrophages and dendritic cells) and certain endothelial cells. They play an important role in uptake and clearance of effete components, such as modified host molecules and apoptotic cells. They bind and internalise micro-organisms and their...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
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2002
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| _version_ | 1826265267276087296 |
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| author | Peiser, L Mukhopadhyay, S Gordon, S |
| author_facet | Peiser, L Mukhopadhyay, S Gordon, S |
| author_sort | Peiser, L |
| collection | OXFORD |
| description | Scavenger receptors (SR) are expressed by myeloid cells (macrophages and dendritic cells) and certain endothelial cells. They play an important role in uptake and clearance of effete components, such as modified host molecules and apoptotic cells. They bind and internalise micro-organisms and their products including Gram-positive bacteria (lipoteichoic acid), Gram-negative bacteria (lipopolysaccharide), intracellular bacteria and CpG DNA. SR can alter cell morphology and their expression is affected by various cytokines. SR are involved in lipid metabolism and bind modified low-density lipoproteins. |
| first_indexed | 2024-03-06T20:21:00Z |
| format | Journal article |
| id | oxford-uuid:2dc71a4e-7e29-48c5-aedf-df85cc4ba756 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T20:21:00Z |
| publishDate | 2002 |
| record_format | dspace |
| spelling | oxford-uuid:2dc71a4e-7e29-48c5-aedf-df85cc4ba7562022-03-26T12:45:05ZScavenger receptors in innate immunity.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:2dc71a4e-7e29-48c5-aedf-df85cc4ba756EnglishSymplectic Elements at Oxford2002Peiser, LMukhopadhyay, SGordon, SScavenger receptors (SR) are expressed by myeloid cells (macrophages and dendritic cells) and certain endothelial cells. They play an important role in uptake and clearance of effete components, such as modified host molecules and apoptotic cells. They bind and internalise micro-organisms and their products including Gram-positive bacteria (lipoteichoic acid), Gram-negative bacteria (lipopolysaccharide), intracellular bacteria and CpG DNA. SR can alter cell morphology and their expression is affected by various cytokines. SR are involved in lipid metabolism and bind modified low-density lipoproteins. |
| spellingShingle | Peiser, L Mukhopadhyay, S Gordon, S Scavenger receptors in innate immunity. |
| title | Scavenger receptors in innate immunity. |
| title_full | Scavenger receptors in innate immunity. |
| title_fullStr | Scavenger receptors in innate immunity. |
| title_full_unstemmed | Scavenger receptors in innate immunity. |
| title_short | Scavenger receptors in innate immunity. |
| title_sort | scavenger receptors in innate immunity |
| work_keys_str_mv | AT peiserl scavengerreceptorsininnateimmunity AT mukhopadhyays scavengerreceptorsininnateimmunity AT gordons scavengerreceptorsininnateimmunity |